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    BIOCAT, LA FUNDACIÓ BIOREGIÓ DE CATALUNYA, com a responsable del tractament, utilitzarà les teves dades amb la finalitat de donar resposta a la teva consulta o petició. Pots accedir, rectificar i suprimir les teves dades, així com exercir altres drets consultant la informació addicional i detallada sobre protecció de dades a la nostra Política de privacitat.







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    Lorem ipsum of Catalonia entrusted Biocat, as a neutral connector and catalyst of the life sciences ecosystem, with a strategic mission: to map all public and private agents working in Advanced Therapies (ATMPs) and to drive the creation of a Hub capable of orchestrating efforts and maximizing impact.

    Fases de desenvolupament
    A
    01

    Discovery and optimization

    1
    1.1

    Cell origin selection

    Selection of CAR structure and gene construct is critical. This includes choosing between single or dual-CAR systems, selecting the appropriate scFv, costimulatory domain(s), linker, and transmembrane domain. Special attention must also be given to the promoter driving CAR expression, as it impacts the level and regulation of CAR expression, which can influence T cell activation, persistence, and safety.

    Descobreix els agents clau
    Cell origin selection Agents clau

    Selection of CAR structure and gene construct is critical. This includes choosing between single or dual-CAR systems, selecting the appropriate scFv, costimulatory domain(s), linker, and transmembrane domain. Special attention must also be given to the promoter driving CAR expression, as it impacts the level and regulation of CAR expression, which can influence T cell activation, persistence, and safety.

    Astra Zeneca
    Astra Zeneca
    Descobrir

    Lorem ipsum through four main lines of work:

    Aplicació de CAR-T en oncologia

    Descobrir

    Desenvolupament de teràpies gèniques

    CAR-T en malalties inflamatòries

    CAR-NK

    CAR-T autòloga